Osteogenesis Imperfecta

What Is Osteogenesis Imperfecta?

Osteogenesis Imperfecta (OI) is a genetic bone disorder characterized by fragile bones that break easily. It is also known as “brittle bone disease.” OI is the result of a mutation (change) in a gene that affects bone formation, bone strength and the structure of other tissues. It is a life-long disorder. OI occurs equally among males and females and in all racial groups. A recent estimate is that approximately 25,000 to 50,000 people in the U.S. have OI. With good medical management and supportive care, the majority of people who have OI will lead healthy, productive lives and can expect an average life span. (OIF)

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Osteogenesis Imperfecta Resources

Below you will find a list of resources that have been invaluable to us in learning about OI. Please let us know if there are resources you think belong on the list.

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